Publication Digest: Real-world evidence bridging clinical trials and routine clinical practice to improve patient care

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Publications Digest. 

In a recent publication, D'Souza et al. examined the role of real-world evidence (RWE) in bridging clinical trials and routine clinical practice. They focused on methodological challenges, emerging analytical approaches, and the value of RWE for healthcare decision-making. The authors highlighted that rigorous study design, transparent reporting, robust protocols, and appropriate scientific oversight are essential for generating reliable RWE. Artificial intelligence may improve data quality, scalability, and reproducibility, but it should remain a supportive rather than autonomous tool. These approaches could strengthen the use of RWE in clinical, regulatory, payer, and healthcare resource-allocation decisions.

Access the full-text article here.