When You May Need a Value Dossier
A value dossier may be useful when the evidence supporting your technology is distributed across journal articles, internal analyses, clinical studies, health economic models and technical materials.
It can support early payer discussions, reimbursement and HTA planning, internal alignment, country adaptation and preparation for formal submissions.
A dossier is particularly valuable when the company needs to explain not only whether the technology works, but also why the disease matters, where current care falls short and what clinical, economic and organizational value the technology may provide.
What Your Team Will Be Able to Communicate
The dossier helps your team explain:
From Scattered Evidence to One Coherent Narrative
A collection of publications does not automatically create a persuasive value story.
A value dossier connects evidence from different sources and explains how the technology may address an unmet need. It provides a common evidence foundation that can be used across market access, reimbursement, HEOR, medical affairs and country teams.
The current MTRC dossier structure includes burden of disease, current treatment options and unmet need, limitations of existing methods, presentation of the technology, clinical evidence and economic outcomes.
How MTRC Works
We clarify whether the dossier will support early payer discussions, reimbursement planning, HTA preparation, internal alignment or country adaptation.
We define the disease burden, unmet need, comparator, technology benefits and evidence questions the dossier must address.
We review the available clinical, economic, epidemiological and organizational evidence and identify any important missing inputs.
We connect the evidence into a logical storyline explaining the healthcare problem, current limitations and potential value of the technology.
We prepare the evidence sections, tables, figures, references and value messages in an agreed structure.
The dossier is reviewed for scientific accuracy, consistency, usability and alignment with the intended reimbursement or HTA context.
Typical Content of a Value Dossier
Epidemiology, morbidity, mortality, quality of life and wider healthcare impact.
Current treatment or diagnostic pathways, guidelines, limitations and remaining patient or system needs.
Description of the technology, mechanism of action, procedure, intended use and place in the pathway.
Evidence relating to safety, effectiveness and relevant patient outcomes.
Costs, resource use, budget impact, cost-effectiveness and potential effects on healthcare delivery.
A clear synthesis of the principal clinical, economic, patient and healthcare-system value messages.
Global, European or Country-Specific Dossiers
Value dossiers are often developed from a global or European perspective and can later be adapted for individual markets.
Clinical-effectiveness evidence will generally draw on the global evidence base, while epidemiology, patient pathways, costs and reimbursement considerations may require European or country-specific data.
Discuss Your Value Dossier
Tell us about your technology, existing evidence, intended audience and target markets.
MTRC will recommend the appropriate dossier format and supporting evidence work.